[Creative PEGWorks 한국공식대리점] Hyaluronic Acid AMCA

어스바이오는 Creative PEGWorks 한국 공식 대리점으로서 모든 제품을 전문적으로 취급 및 공급하고 있습니다.
Creative PEGWorks의 AMCA Hyaluronic Acid 제품을 소개드립니다.
 

Product Information:

Hyaluronic Acid is labeled with AMCA (aminomethyl coumarin acetate). AMCA is a blue fluorescent dye (Excitation: 345-350 nm, Emission: 440-460 nm). Purity: >95% lyophilized powder. Degree of substitution: 1 mol % substitution and at least one dye molecule per HA polymer.

Properties

• Name and Source: Hyaluronic acid (HA, Hyaluronan, Hyaluronate) is an anionic, non-sulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. CAS# 9004-61-9. 
• Appearance: Lyophilized powder. The color depends on the color of the dye and the dye labeling ratio.
• Solubility: Soluble in water and the solubility data varies with MW. Higher MW results in lowered solubility. Typically solubility ranges 5-50 mg/mL, that is, 0.5%-5%. Buffered solution at pH >6 enhances solubility due to deprotonation of carboxylic acid groups and formation of carboxylate salts. HA derivatives with hydrophobic groups will lower the solubility in water, and adding alcohol or DMSO to an alcohol-water or DMSO-water mixture can dramatically improve the solubility up to 200 mg/mL (20%).
• Degree of Substitution (DoS): The standard DoS is 1% by default. Product variants with special DoS other than 1% is indicated in the product name and catalog number. For example, HA-635-2% means that the DoS is 2% for this particular product.

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